Article
Genotypic and phenotypic correlates of the HIV Type 1 env gene evolution in infected children with discordant response to antiretroviral therapy.
AIDS research and human retroviruses - 1 Dec 2004
Bagnarelli Patrizia, Vecchi Manuela, Burighel Nicoletta, Bellanova Domenico, Menzo Stefano, Clementi Massimo, De Rossi Anita
Abstract excerpt
The genotypic-phenotypic correlates of human immunodeficiency virus type 1 (HIV-1) env gene evolution were investigated in samples from eight infected children under antiretroviral therapy (ART) and virological failure. Evolution of the gp120 C2-V5 env sequence was demonstrated in all subjects but one by sequence analysis of the replicating plasma virus collected at baseline and 12-15 months after ART initiation....
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