Article
CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia.
Journal of virology - 1 Feb 2005
Blaak H, Boers P H M, Gruters R A, Schuitemaker H, van der Ende M E, Osterhaus A D M E
Abstract excerpt
Human immunodeficiency virus type 2 (HIV-2) is generally considered capable of using a broad range of coreceptors. Since HIV-2 variants from individuals with nonprogressive infection were not studied previously, the possibility that broad coreceptor usage is a property of variants associated with progressive infection could not be excluded. To test this, we determined the coreceptor usage of 43 HIV-2 variants...
Topics
- Cell Line, Tumor
- Genetic Variation
- HIV Infections
- HIV Long-Term Survivors
- HIV-2
- Humans
- Receptors, CCR5
- Receptors, CXCR6
- Receptors, Chemokine
- Receptors, Cytokine
- Receptors, G-Protein-Coupled
- Receptors, HIV
- Receptors, Peptide