Article
No association between the Arg201Gly polymorphism of the DCC gene and colorectal cancer.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Dec 2004
de Jong M M, te Meerman G J, van der Graaf W T A, de Vries E G E, Nolte I M, Mulder M J, Bruinenberg M, van der Steege G, Schaapveld M, Sijmons R H, Hofstra R M W, Kleibeuker J H
Abstract excerpt
BACKGROUND AND AIMS: In one small study, the DCC Arg201Gly polymorphism has been observed more frequently in colorectal cancer cases compared with controls. We wondered whether these results could be replicated in a much larger study. METHODOLOGY: The DCC Arg201 Gly polymorphism was genotyped in 625 unselected Caucasian colorectal cancer patients and 220 controls. Association analysis was used to search for a...
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