Article
intersex, a gene required for female sexual development in Drosophila, is expressed in both sexes and functions together with doublesex to regulate terminal differentiation.
Development (Cambridge, England) - 1 Oct 2002
Garrett-Engele Carrie M, Siegal Mark L, Manoli Devanand S, Williams Byron C, Li Hao, Baker Bruce S
Abstract excerpt
Previous genetic studies indicated intersex (ix) functions only in females and that it acts near the end of the sex determination hierarchy to control somatic sexual differentiation in Drosophila melanogaster. We have cloned ix and characterized its function genetically, molecularly and biochemically. The ix pre-mRNA is not spliced, and ix mRNA is produced in both sexes. The ix gene encodes a 188 amino acid...
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