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Article

Chromosomal translocations and sarcomas

1 Jul 2002

Abstract excerpt

This review examines how the identification of tumor-specific translocations and fusion proteins has advanced the basic scientific and clinical understanding of sarcomas. Recent genetic advances, including the ASPL-TFE3 fusion of alveolar soft part sarcoma, the JAZF1-JJAZ1 fusion of endometrial stromal sarcoma, and HMGIC fusions in liposarcoma, are discussed. Next, the review addresses the ways in which molecular...

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PMID: 12130926
DOI: 10.1097/00001622-200207000-00008

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