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Article

Mediastinal Synovial Sarcoma: Clinicopathologic Analysis of 21 Cases With Molecular Confirmation.

The American journal of surgical pathology - 1 Jun 2018

Terra Simone B S P, Aesif Scott W, Maleszewski Joseph J, Folpe Andrew L, Boland Jennifer M

Abstract excerpt

Synovial sarcoma (SS), a translocation-associated sarcoma characterized by SS18-SSX1/2 fusion, presents most often in the extremities of young adults. While SS regularly occurs in the pleuropulmonary parenchyma, the mediastinum is an exceedingly rare primary site; the literature on this subject is predominantly composed of case reports and small series, mostly without molecular confirmation. Cases of mediastinal...

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Topics

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Share to Cell Differentiation
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Mediastinal Neoplasms

Share to Oncogene Proteins, Fusion

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Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Tomography, X-Ray Computed

Source

Identifiers

PMID: 29543673
DOI: 10.1097/PAS.0000000000001050

Genes

SSX1
SSX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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