Article
An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children.
Lancet (London, England) - 1 Jan 2000
Heaton T, Rowe J, Turner S, Aalberse R C, de Klerk N, Suriyaarachchi D, Serralha M, Holt B J, Hollams E, Yerkovich S, Holt K, Sly P D, Goldblatt J, Le Souef P, Holt P G
Abstract excerpt
BACKGROUND: Increasing evidence suggests that patterns of T-cell immunity to inhalant allergens in genetically diverse human populations are more heterogeneous than previously assumed, and that covert differences in expression patterns might underlie variations in airway disease phenotypes. We tested this proposition in a community sample of children. METHODS: We analysed data from 172 individuals who had been...
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