Article
Immune mechanisms and development of childhood asthma.
The Lancet. Respiratory medicine - 1 Aug 2014
Raedler Diana, Schaub Bianca
Abstract excerpt
Early life influences are crucial for the development of distinct childhood asthma phenotypes, which are currently included under the term asthma syndrome. Improved characterisation of different childhood asthma phenotypes will help to elucidate specific underlying immune mechanisms--namely, endotypes. Besides genetics, epigenetics and environmental factors have an effect on innate and adaptive immune regulatory...
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