Article
Childhood asthma: Novel endotyping by cytokines, validated through sensitization profiles and clinical characteristics.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 2021
Salvermoser Michael, Zeber Kathrin, Boeck Andreas, Klucker Elisabeth, Schaub Bianca
Abstract excerpt
BACKGROUND: Specific allergy sensitization pattern, using "component-resolved diagnosis" (CRD), is a central component of allergy and asthma in childhood. Besides this, allergic asthma has been characterized by a Th2-shifted endotype with elevation of classical Th2 cytokines. Recently, other endotypes with distinct mechanisms focusing on cytokine regulation evolved, yet those pathways are still not well...
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