Article
Multiple atopy phenotypes and their associations with asthma: similar findings from two birth cohorts.
Allergy - 1 Jun 2013
Lazic N, Roberts G, Custovic A, Belgrave D, Bishop C M, Winn J, Curtin J A, Hasan Arshad S, Simpson A
Abstract excerpt
BACKGROUND: Although atopic sensitization is one of the strongest risk factors for asthma, its relationship with asthma is poorly understood. We hypothesize that 'atopy' encompasses multiple sub-phenotypes that relate to asthma in different ways. METHODS: In two population-based birth cohorts (Manchester and Isle of Wight - IoW), we used a machine learning approach to independently cluster children into different...
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