Article
Prototypic disorders of gastrointestinal mucosal immune function: Celiac disease and Crohn's disease.
The Journal of allergy and clinical immunology - 1 Jan 2005
James Stephen P
Abstract excerpt
Celiac disease is a disorder of the small intestine characterized by chronic inflammation of the mucosa and protean clinical manifestations caused by loss of tolerance to dietary antigens. Two strongly associated cofactors have been identified: the presence of HLA-DQ2 or HLA-DQ8 in the host and specific antigenic peptides in the diet that are present in wheat, rye, and barley. Most patients have complete...
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