Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients.

Journal of clinical microbiology - 1 Jan 2005

Springer Kathryn L, Chou Sunwen, Li Shaobing, Giller Roger H, Quinones Ralph, Shira James E, Weinberg Adriana

Abstract excerpt

Infection with cytomegalovirus (CMV) remains a significant cause of morbidity and mortality among hematopoietic cell transplant (HCT) recipients. We describe two pediatric HCT recipients who developed persistent and severe drug-resistant CMV infections. CMV resistance to foscarnet and ganciclovir was detected after only 6 and 11 weeks of therapy, respectively. Viral pol mutations associated with drug resistance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus
Share to Cytomegalovirus Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Fatal Outcome

Share to Foscarnet

Share to Ganciclovir

Share to Gene Products, pol

Share to Hematopoietic Stem Cell Transplantation

Source

Open in PubMed Open full text

Identifiers

PMID: 15634973
DOI: 10.1128/JCM.43.1.208-213.2005
PMCID: PMC540138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients.PMID 15634973Read ↗

The biology of cytomegalovirus drug resistance.Semantic proximity Read ↗

Drug-resistant cytomegalovirus: clinical implications of specific mutations.Semantic proximity Read ↗

Cytomegalovirus drug resistance.Semantic proximity Read ↗

Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.Semantic proximity Read ↗

Prevalence of cytomegalovirus antiviral drug resistance in transplant recipients.Semantic proximity Read ↗

Characterization of the dynamics of human cytomegalovirus resistance to antiviral drugs by ultra-deep sequencing.Semantic proximity Read ↗

Cytomegalovirus (CMV) resistance to antivirals.Semantic proximity Read ↗

Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus.Semantic proximity Read ↗

Antiviral drug resistance in human cytomegalovirus.Semantic proximity Read ↗

Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.Semantic proximity Read ↗

"The end of innocence" revisited: resistance of herpesviruses to antiviral drugs.Semantic proximity Read ↗

Intra-host diversity of drug-resistant cytomegalovirus: A case report of cytomegalovirus infection after allogeneic hematopoietic cell transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.