Article
Counting alleles in single lesions of prostate tumors from ethnically diverse patients.
The Prostate - 15 Feb 2008
Morikawa Aki, Varma Vijay, Gillespie Theresa W, Lyles Robert H, Goodman Michael, Bostick Roberd M, Mandel Jack S, Zhou Wei
Abstract excerpt
BACKGROUND: The presence of racial disparities in incidence and mortality rates are well-documented for prostate cancer. Nevertheless, it is unclear whether such disparities are due to genetic alterations that are involved in prostate cancer initiation. Here, we evaluated chromosome 8p allelic loss in a racially diverse cohort. METHODS: Laser-capture microdissection was used to isolate tumors cells from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
