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Article

Inflammatory diseases: is ubiquitinated NEMO at the hub?

Current biology : CB - 29 Dec 2004

Burns Kimberly A, Martinon Fabio

Abstract excerpt

Many patients with Crohn's disease carry mutations in NOD2, a molecule that can both activate and attenuate the pro-inflammatory effects of NF-kappa B. Recent studies implicate NOD2-induced ubiquitination of the NF-kappa B regulator NEMO as a potential means of manipulating the NF-kappa B signal.

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Source

Identifiers

PMID: 15620634
DOI: 10.1016/j.cub.2004.11.040

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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