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Article

Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated disease.

Biochimica et biophysica acta - 1 Nov 2012

Tigno-Aranjuez Justine T, Abbott Derek W

Abstract excerpt

The immune system is exquisitely balanced. It has the ability to effectively respond to and control infections while at the same time preventing inappropriate responses to self and environmental antigens. When this response goes awry, either through a failure to activate the immune response, or failure to terminate it, inflammatory pathology results. Posttranslational modifications (PTMs) such as ubiquitination...

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Source

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Identifiers

PMID: 22522061
DOI: 10.1016/j.bbamcr.2012.03.017
PMCID: PMC3404158

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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