Article
The PerR regulon in peroxide resistance and virulence of Streptococcus pyogenes.
Molecular microbiology - 1 Jan 2005
Brenot Audrey, King Katherine Y, Caparon Michael G
Abstract excerpt
Prior studies have shown that the catalase-deficient pathogen Streptococcus pyogenes (group A streptococcus) has a robust ability to resist oxidative stress that partially involves the transcriptional regulator PerR. However, the extent of the PerR regulon and the contribution of the members of this regulon to virulence are unknown. In this study, DNase I footprinting revealed that PerR binds specifically to a...
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