Article
Aerotolerance and peroxide resistance in peroxidase and PerR mutants of Streptococcus pyogenes.
Journal of bacteriology - 1 Oct 2000
King K Y, Horenstein J A, Caparon M G
Abstract excerpt
Survival in aerobic conditions is critical to the pathogenicity of many bacteria. To investigate the means of aerotolerance and resistance to oxidative stress in the catalase-negative organism Streptococcus pyogenes, we used a genomics-based approach to identify and inactivate homologues of two peroxidase genes, encoding alkyl hydroperoxidase (ahpC) and glutathione peroxidase (gpoA). Single and double mutants...
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