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Article

Phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin alpha.

The Journal of biological chemistry - 18 Mar 2005

Chen Min-Hsuan, Ben-Efraim Iris, Mitrousis Gregory, Walker-Kopp Nancy, Sims Peter J, Cingolani Gino

Abstract excerpt

Nuclear import of proteins containing a classical nuclear localization signal (NLS) is an energy-dependent process that requires the heterodimer importin alpha/beta. Three to six basic contiguous arginine/lysine residues characterize a classical NLS and are thought to form a basic patch on the surface of the import cargo. In this study, we have characterized the NLS of phospholipid scramblase 1 (PLSCR1), a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15611084
DOI: 10.1074/jbc.M413194200

Genes

PLSCR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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