Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus

23 Feb 2009

Abstract excerpt

The Plasmodium falciparum genome encodes a single calpain. By generating P. falciparum clones expressing C-terminally tagged calpain, we localized this protein to the nucleolus. Pf_calpain possesses an unusual and long N-terminal domain in which we identified three subregions that are highly conserved among Plasmodium species. Two have putative targeting signals: a myristoylation motif and a nuclear localization...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calpain Protease Function and Regulation
Share to Mosquito-borne diseases and control
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19239622
DOI: 10.1111/j.1365-2958.2009.06639.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolusPMID 19239622Read ↗

Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparumSemantic proximity Read ↗

Phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin alpha.Semantic proximity Read ↗

Identification and characterization of nuclear localization signals of CaMKP-N.Semantic proximity Read ↗

The C2 domain of calpain 5 contributes to enzyme activation and membrane localization.Semantic proximity Read ↗

Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology.Semantic proximity Read ↗

The Ins and Outs of Nuclear Trafficking: Unusual Aspects in Apicomplexan ParasitesSemantic proximity Read ↗

The Nucleoporin MLP1 of the nuclear basket is essential for nuclear integrity and ploidy maintenance in <i>Trypanosoma brucei</i>Semantic proximity Read ↗

Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane.Semantic proximity Read ↗

The prenylation status of a novel plant calmodulin directs plasma membrane or nuclear localization of the protein.Semantic proximity Read ↗

Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants.Semantic proximity Read ↗

Molecular determinants of ciliary membrane localization of Trypanosoma cruzi flagellar calcium-binding protein.Semantic proximity Read ↗

Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.