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Article

Genotypic confirmation from the original dried blood specimens in a neonatal hemoglobinopathy screening program.

Pediatric research - 1 Mar 1992

Descartes M, Huang Y, Zhang Y H, McCabe L L, Gibbs R, Therrell B L, McCabe E R

Abstract excerpt

Dried blood spots are used for newborn screening because of ease of sample collection, handling, and shipment. DNA is stable and accessible in the filter paper matrix. Genotypic confirmation using initial specimens is demonstrated for a regional screening program. Seventy-five blinded samples underwent DNA analysis after Hb electrophoresis. DNA was microextracted from a 1/2-inch semicircle (25 microL whole blood...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1561006
DOI: 10.1203/00006450-199203000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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