Article
Lack of association between VNTR polymorphism of dopamine transporter gene (SLC6A3) and schizophrenia in a Brazilian sample.
Arquivos de neuro-psiquiatria - 1 Dec 2004
Cordeiro Quirino, Talkowski Michael, Wood Joel, Ikenaga Eliza, Vallada Homero
Abstract excerpt
A role of dopaminergic dysfunction has been postulated in the aetiology of schizophrenia. We hypothesized that variations in the dopamine transporter gene (SLC6A3) may be associated with schizophrenia. We conducted case-control and family based analysis on the polymorphic SLC6A3 variable number tandem repeat (VNTR) in a sample of 220 schizophrenic patients, 226 gender and ethnic matched controls, and 49...
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