Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specific polyunsaturated fatty acids drive TRPV-dependent sensory signaling in vivo.

Cell - 17 Dec 2004

Kahn-Kirby Amanda H, Dantzker Jami L M, Apicella Alfonso J, Schafer William R, Browse John, Bargmann Cornelia I, Watts Jennifer L

Abstract excerpt

A variety of lipid and lipid-derived molecules can modulate TRP cation channel activity, but the identity of the lipids that affect TRP channel function in vivo is unknown. Here, we use genetic and behavioral analysis in the nematode C. elegans to implicate a subset of 20-carbon polyunsaturated fatty acids (PUFAs) in TRPV channel-dependent olfactory and nociceptive behaviors. Olfactory and nociceptive TRPV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arachidonic Acid
Share to Behavior, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caenorhabditis elegans

Share to Calcium Channels

Share to Eicosapentaenoic Acid

Share to Fatty Acids, Omega-6

Share to Ion Channel Gating

Share to Sensation Disorders

Source

Identifiers

PMID: 15607983
DOI: 10.1016/j.cell.2004.11.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specific polyunsaturated fatty acids drive TRPV-dependent sensory signaling in vivo.PMID 15607983Read ↗

Juniperonic Acid Biosynthesis is Essential in Caenorhabditis Elegans Lacking Δ6 Desaturase (fat-3) and Generates New ω-3 Endocannabinoids.Semantic proximity Read ↗

The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegansSemantic proximity Read ↗

Deficiencies in C20 polyunsaturated fatty acids cause behavioral and developmental defects in Caenorhabditis elegans fat-3 mutants.Semantic proximity Read ↗

Stress response pathways protect germ cells from omega-6 polyunsaturated fatty acid-mediated toxicity in Caenorhabditis elegans.Semantic proximity Read ↗

Fatty acid metabolic reprogramming promotes <i>C. elegans</i> developmentSemantic proximity Read ↗

Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans.Semantic proximity Read ↗

Application of Caenorhabditis elegans in Lipid Metabolism ResearchSemantic proximity Read ↗

Obesity and the regulation of fat metabolismSemantic proximity Read ↗

Cannabinoids Activate the Insulin Pathway to Modulate Mobilization of Cholesterol in <i>C. elegans</i>Semantic proximity Read ↗

Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol.Semantic proximity Read ↗

Genes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegans.Semantic proximity Read ↗

Fatty acid composition and gene expression profiles are altered in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.