Article
Solution structure of the active-centre mutant I14A of the histidine-containing phosphocarrier protein from Staphylococcus carnosus.
European journal of biochemistry - 1 Dec 2004
Möglich Andreas, Koch Brigitte, Gronwald Wolfram, Hengstenberg Wolfgang, Brunner Eike, Kalbitzer Hans Robert
Abstract excerpt
High-pressure NMR experiments performed on the histidine-containing phosphocarrier protein (HPr) from Staphylococcus carnosus have shown that residue Ile14, which is located in the active-centre loop, exhibits a peculiarly small pressure response. In contrast, the rest of the loop shows strong pressure effects as is expected for typical protein interaction sites. To elucidate the structural role of this residue,...
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