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Article

Functional consequences of the prothrombotic SERPINC1 rs2227589 polymorphism on antithrombin levels.

Haematologica - 1 Apr 2009

Antón Ana I, Teruel Raúl, Corral Javier, Miñano Antonia, Martínez-Martínez Irene, Ordóñez Adriana, Vicente Vicente, Sánchez-Vega Beatriz

Abstract excerpt

Genetic factors involved in the interindividual variability of antithrombin have not been identified. We studied two polymorphisms of the gene coding for antithrombin (SER-PINC1) in 298 Spanish Caucasian blood donors: rs3138521, a DNA length polymorphism located on the promoter region and rs2227589, a SNP located on intron 1 that has been described as a mild thrombotic risk factor. We detected a complete linkage...

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Source

Open in PubMed Open full text

Identifiers

PMID: 19229049
DOI: 10.3324/haematol.2008.000604
PMCID: PMC2663624

Genes

SERPINC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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