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Article

Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence.

Journal of virology - 1 Mar 2003

Wang Fu-Zhang, Akula Shaw M, Sharma-Walia Neelam, Zeng Ling, Chandran Bala

Abstract excerpt

Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma-associated herpesvirus, implicated in the pathogenesis of Kaposi's sarcoma, utilizes heparan sulfate-like molecules to bind the target cells via its envelope-associated glycoproteins gB and gpK8.1A. HHV-8-gB possesses the Arg-Gly-Asp (RGD) motif, the minimal peptide region of many proteins known to interact with subsets of host cell surface integrins. HHV-8 utilizes...

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Identifiers

PMID: 12584338
DOI: 10.1128/jvi.77.5.3131-3147.2003
PMCID: PMC149745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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