Article
The Neutralizing Linear Epitope of Human Herpesvirus 6A Glycoprotein B Does Not Affect Virus Infectivity.
Journal of virology - 1 Mar 2018
Wakata Aika, Kanemoto Satoshi, Tang Huamin, Kawabata Akiko, Nishimura Mitsuhiro, Jasirwan Chyntia, Mahmoud Nora Fahmy, Mori Yasuko
Abstract excerpt
Human herpesvirus 6A (HHV-6A) glycoprotein B (gB) is a glycoprotein consisting of 830 amino acids and is essential for the growth of the virus. Previously, we reported that a neutralizing monoclonal antibody (MAb) called 87-y-13 specifically reacts with HHV-6A gB, and we identified its epitope residue at asparagine (Asn) 347 on gB. In this study, we examined whether the epitope recognized by the neutralizing MAb...
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