Article
Molecular characterization of human immunodeficiency virus type 1 isolates from Venezuela.
AIDS research and human retroviruses - 1 May 1995
Quiñones-Mateu M E, Dopazo J, Esté J A, Rota T R, Domingo E
Abstract excerpt
Eight HIV-1 isolates from Venezuela have been characterized by nucleotide sequencing of the entire reverse transcriptase (RT)- and surface glycoprotein (gp 120)-coding regions. Average mutant frequencies were 2.5 x 10(-2) substitutions per nucleotide (s/nt) for the RT-coding region, and 10 x 10(-2) or 6.8 x 10(-2) s/nt for the gp120-coding region, depending on whether gaps introduced for optimal alignment were or...
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