Article
Phylogenetic analysis of gag genes from 70 international HIV-1 isolates provides evidence for multiple genotypes.
AIDS (London, England) - 1 Jun 1993
Louwagie J, McCutchan F E, Peeters M, Brennan T P, Sanders-Buell E, Eddy G A, van der Groen G, Fransen K, Gershy-Damet G M, Deleys R
Abstract excerpt
OBJECTIVE: To determine the extent of genetic variation among internationally collected HIV-1 isolates, to analyse phylogenetic relationships and the geographic distribution of different variants. DESIGN: Phylogenetic comparison of 70 HIV-1 isolates collected in 15 countries on four continents. METHODS: To sequence the complete gag genome of HIV-1 isolates, build multiple sequence alignments and construct...
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