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Article

Mitochondrial ND5 mutations in idiopathic Parkinson's disease.

Biochemical and biophysical research communications - 21 Jan 2005

Parker W Davis, Parks Janice K

Abstract excerpt

Idiopathic Parkinson's disease (PD) is characterized by a systemic loss of activity of complex I (NADH:ubiquinone oxidoreductase), the target enzyme of the parkinsonism producing neurotoxin, MPTP. Cybrid experiments strongly suggest that the loss of complex I activity arises from mitochondrial DN...

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Identifiers

PMID: 15596151
DOI: 10.1016/j.bbrc.2004.11.093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15596151-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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