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Article

Altered protein dynamics of disease-associated lamin A mutants.

BMC cell biology - 13 Dec 2004

Gilchrist Susan, Gilbert Nick, Perry Paul, Ostlund Cecilia, Worman Howard J, Bickmore Wendy A

Abstract excerpt

BACKGROUND: Recent interest in the function of the nuclear lamina has been provoked by the discovery of lamin A/C mutations in the laminopathy diseases. However, it is not understood why mutations in lamin A give such a range of tissue-specific phenotypes. Part of the problem in rationalising gen...

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Identifiers

PMID: 15596010
DOI: 10.1186/1471-2121-5-46
PMCID: PMC539277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15596010-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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