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Article

In silico fine-mapping: narrowing disease-associated loci by intergenomics.

Bioinformatics (Oxford, England) - 15 Apr 2005

Serrano-Fernández Pablo, Ibrahim Saleh M, Koczan Dirk, Zettl Uwe K, Möller Steffen

Abstract excerpt

UNLABELLED: Genetic linkage and association studies define quantitative trait loci (QTLs) and susceptibility loci (SLs) that influence the phenotype of polygenic traits. A web-accessible application was created to identify intergenomic consensuses to fine map QTLs and SLs in silico and select particularly promising candidate genes for such traits. Furthermore, this approach offers an empirical evaluation of...

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PMID: 15591355
DOI: 10.1093/bioinformatics/bti209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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