Article
1059G/C polymorphism within the exon 2 of the C-reactive protein gene: relationship to C-reactive protein levels and prognosis in unstable angina.
Coronary artery disease - 1 Nov 2007
Rizzello Vittoria, Liuzzo Giovanna, Giannuario Giovanna Di, Trabetti Elisabetta, Brugaletta Salvatore, Santamaria Matteo, Piro Maddalena, Pignatti Pier Franco, Maseri Attilio, Biasucci Luigi M, Crea Filippo
Abstract excerpt
OBJECTIVE: Patients with unstable angina (UA) and high C-reactive protein (CRP) have increased cardiovascular risk. Whether genetic factors such as the synonymous 1059G/C polymorphism within the exon 2 of the human CRP gene determine CRP levels and outcome is unclear. METHODS: In 105 consecutive patients with UA, we assessed the CRP 1059G/C polymorphism, CRP plasma levels and interleukin-6 production after...
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