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Article

Central Nervous System Damage, Monocytes and Macrophages, and Neurological Disorders in AIDS

1 Mar 2002

Abstract excerpt

This review focuses on the role of the extended macrophage/monocyte family in the central nervous system during HIV or SIV infection. The accumulated data, buttressed by recent experimental results, suggest that these cells play a central, pathogenic role in retroviral-associated CNS disease. While the immune system is able to combat the underlying retroviral infection, the accumulation and widespread activation...

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PMID: 12052920
DOI: 10.1146/annurev.neuro.25.112701.142822

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