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Article

Predicted genotypic resistance to the novel entry inhibitor, BMS-378806, among HIV-1 isolates of subtypes A to G.

AIDS (London, England) - 19 Nov 2004

Moore Penny L, Cilliers Tonie, Morris Lynn

Abstract excerpt

BMS-378806 targets virus entry by inhibiting the binding of HIV-1 gp120 to the CD4 receptor. Env sequences (n = 1226) of subtypes A-G were analysed to determine the frequency of mutations associated with resistance to BMS-378806. In line with reported sensitivity data, background genotypic resistance to BMS-378806 among non-B HIV-1 viruses was found to be higher than in subtype B. These data suggest that...

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PMID: 15577547
DOI: 10.1097/00002030-200411190-00015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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