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Article

HIV gp120 H375 is unique to HIV-1 subtype CRF01_AE and confers strong resistance to the entry inhibitor BMS-599793, a candidate microbicide drug.

Antimicrobial agents and chemotherapy - 1 Aug 2012

Schader Susan M, Colby-Germinario Susan P, Quashie Peter K, Oliveira Maureen, Ibanescu Ruxandra-Ilinca, Moisi Daniela, Mespléde Thibault, Wainberg Mark A

Abstract excerpt

BMS-599793 is a small molecule entry inhibitor that binds to human immunodeficiency virus type 1 (HIV-1) gp120, resulting in the inhibition of CD4-dependent entry into cells. Since BMS-599793 is currently considered a candidate microbicide drug, we evaluated its efficacy against a number of primary patient HIV isolates from different subtypes and circulating recombinant forms (CRFs) and showed that activity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22615295
DOI: 10.1128/AAC.00639-12
PMCID: PMC3421599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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