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Article

Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast.

Molecular biology of the cell - 1 Aug 2002

Henry Kenneth R, D'Hondt Kathleen, Chang JiSuk, Newpher Thomas, Huang Kristen, Hudson R Tod, Riezman Howard, Lemmon Sandra K

Abstract excerpt

SCD5 was identified as a multicopy suppressor of clathrin HC-deficient yeast. SCD5 is essential, but an scd5-Delta338 mutant, expressing Scd5p with a C-terminal truncation of 338 amino acids, is temperature sensitive for growth. Further studies here demonstrate that scd5-Delta338 affects receptor-mediated and fluid-phase endocytosis and normal actin organization. The scd5-Delta338 mutant contains larger and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12181333
DOI: 10.1091/mbc.e02-01-0012
PMCID: PMC117929

Genes

SCD5
HIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast.PMID 12181333Read ↗

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