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Article

Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders.

Blood reviews - 1 Jan 2005

Kralovics Robert, Skoda Radek C

Abstract excerpt

We summarize the current knowledge on molecular alterations in myeloproliferative disorders (MPD), in particular altered in vitro responses of progenitor cells, cytokine signaling, gene expression patterns and genetic lesions. Newly characterized markers, such as altered expression of polycythemia rubra vera-1 (PRV-1) and the thrombopoietin receptor (c-MPL) as well as deletions on chromosome 20q (del20q) and loss...

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Source

Identifiers

PMID: 15572213
DOI: 10.1016/j.blre.2004.02.002

Genes

MPL
EPO
TPO
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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