Article
Complex translocation (8;12;21): a new variant of t(8;21) in acute myeloid leukemia.
Cancer genetics and cytogenetics - 1 Dec 2004
Farra C, Awwad J, Valent A, Lozach F, Bernheim A
Abstract excerpt
Variants of the t(8;21)(q22;q22) involving chromosomes 8, 21, and other chromosomes account for approximately 3% of all t(8;21)(q22;q22) in acute myeloid leukemia (AML) patients. In this paper, we report a case of AML-M2 with a t(8;12;21)(q22;p12 approximately p13;q22) associated with chromosomal abnormalities, including loss of the Y chromosome and trisomy 8q22 approximately qter. Using a dual-color fluorescence...
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