Article
Genetic analysis of 8;21 chromosomal translocation without AML1 gene involvement in MDS-AML.
British journal of haematology - 1 Dec 1997
Kawano S, Miyanishi S, Shimizu K, Tanaka K, Okumura A, Ohki M, Kamada N, Ohno Y
Abstract excerpt
We have investigated a case of acute myelocytic leukaemia derived from myelodysplastic syndrome (MDS-AML) with an 8;21 translocation. In this case the AML1/MTG8 (ETO) fusion transcript was not detected by reverse transcriptase-polymerase chain reaction (RT-PCR), and the rearrangement of the AML1...
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