CD34+ cells from acute myeloid leukemia, myelodysplastic syndromes, and normal bone marrow display different apoptosis and drug resistance-associated phenotypes.

doi:10.1158/1078-0432.CCR-04-0598

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Article

CD34+ cells from acute myeloid leukemia, myelodysplastic syndromes, and normal bone marrow display different apoptosis and drug resistance-associated phenotypes.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2004

Suárez Lilia, Vidriales María-Belén, García-Laraña José, Sanz Guillermo, Moreno María-José, López Antonio, Barrena Susana, Martínez Rafael, Tormo Mar, Palomera Luis, Lavilla Esperanza, López-Berges Ma Consuelo, de Santiago María, de Equiza M Encarnación Pérez, Miguel Jesús F San, Orfao Alberto

Abstract excerpt

Myelodysplastic syndromes and acute myeloid leukemia (AML) are heterogeneous disorders in which conflicting results in apoptosis and multidrug resistance (MDR) have been reported. We have evaluated by multiparameter flow cytometry the expression of apoptosis- (APO2.7, bcl-2, and bax) and MDR-related proteins [P-glycoprotein (P-gp), multidrug resistance protein (MRP), and lung resistance protein (LRP)]...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

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PMID: 15569991
DOI: 10.1158/1078-0432.CCR-04-0598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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