Article
Multiparametric analysis of apoptotic and multi-drug resistance phenotypes according to the blast cell maturation stage in elderly patients with acute myeloid leukemia.
Haematologica - 1 Dec 2001
Suárez L, Vidriales B, García-Laraña J, López A, Martínez R, Martín-Reina V, Tormo M, González-San Miguel J D, Lavilla E, García-Boyero R, Orfao A, San Miguel J F
Abstract excerpt
BACKGROUND AND OBJECTIVES: Acute myeloid leukemia (AML) is a heterogeneous group of malignant diseases, often characterized by coexistence of more than one subpopulation of blast cells. Multiparametric flow cytometry immunophenotyping has proven to be a reliable and sensitive approach for the discrimination of myeloid blast cells from residual normal cells present in bone marrow samples from AML patients and, at...
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