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Article

Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment

1 Dec 1998

Abstract excerpt

Apoptosis (programmed cell death) is an active cellular process which regulates cell population size by decreasing cell survival. In this review the underlying cellular and molecular mechanisms of apoptosis in hemopoietic and non-hemopoietic cells are described, with specific focus on these issues in the myelodysplastic syndrome (MDS), a myeloid clonal hemopathy. Apoptosis-regulating genes exist as families whose...

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PMID: 9922076
DOI: 10.1016/s0145-2126(98)00112-x

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