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Prenatal Environmental Tobacco Smoke Exposure Promotes Adult Atherogenesis and Mitochondrial Damage in Apolipoprotein E <sup>−/−</sup> Mice Fed a Chow Diet

30 Nov 2004

Abstract excerpt

BACKGROUND: Environmental tobacco smoke (ETS) exposure is recognized as a cardiovascular disease risk factor; however, the impact of prenatal ETS exposure on adult atherogenesis has not been examined. We hypothesized that in utero ETS exposure promotes adult atherosclerotic lesion formation and mitochondrial damage. METHODS AND RESULTS: Atherosclerotic lesion formation, mitochondrial DNA damage, antioxidant...

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PMID: 15569831
DOI: 10.1161/01.cir.0000149747.82157.01

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