Article
Alterations in the TGFbeta signaling pathway in myogenic progenitors with age.
Aging cell - 1 Dec 2004
Beggs Marjorie L, Nagarajan Radhakrishnan, Taylor-Jones Jane M, Nolen Greg, Macnicol Melanie, Peterson Charlotte A
Abstract excerpt
Myogenic progenitors in adult muscle are necessary for the repair, maintenance and hypertrophy of post-mitotic muscle fibers. With age, fat deposition and fibrosis contribute to the decline in the integrity and functional capacity of muscles. In a previous study we reported increased accumulation...
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