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Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine

1 Nov 2004

Abstract excerpt

A 94C>A missense mutation in the ITPA gene which encodes inosine triphosphate pyrophosphatase has been associated with adverse effects from azathioprine, specifically flu-like symptoms, pancreatitis and rash. We hypothesized that this association may also be present in a larger, population-based group of inflammatory bowel disease patients intolerant of thiopurine drugs. We performed genotyping for this...

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PMID: 15564886
DOI: 10.1097/00008571-200411000-00010

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Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprinePMID 15564886Read ↗

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