Article
Endurance training-induced changes in the insulin response to oral glucose are associated with the peroxisome proliferator-activated receptor-gamma2 Pro12Ala genotype in men but not in women.
Metabolism: clinical and experimental - 1 Jan 2005
Weiss Edward P, Kulaputana Onanong, Ghiu Ioana A, Brandauer Josef, Wohn Christopher R, Phares Dana A, Shuldiner Alan R, Hagberg James M
Abstract excerpt
The present study sought to investigate, in sedentary men and women, (a) whether a common functional gene variant (peroxisome proliferator-activated receptor-gamma2 [PPARgamma2] Pro12Ala) predicts insulin action and (b) whether improvements in insulin action in response to endurance exercise training are associated with PPARgamma2 Pro12Ala. Sedentary, 50- to 75-year-old men and women (N = 73) were genotyped and...
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