Article
Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?
Metabolism: clinical and experimental - 1 Jan 2004
Franks P W, Luan J, Browne P O, Harding A-H, O'Rahilly S, Chatterjee V K K, Wareham N J
Abstract excerpt
Peroxisome proliferator-activated receptor gamma (PPARgamma) has a role in controlling adipogenesis and insulin sensitivity. Previous studies have suggested that a common polymorphism (Pro12Ala) in the PPARgamma-2 isoform of this gene may be associated with markers of insulin resistance. We have previously shown that in combination, the relationships with fasting insulin of dietary polyunsaturated to saturated...
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