Article
The Elston-Stewart algorithm for continuous genotypes and environmental factors.
Human heredity - 1 Jan 1992
Elston R C, George V T, Severtson F
Abstract excerpt
The Elston-Stewart algorithm for a normally distributed trait under a polygenic model is explained in detail and extended to allow for other continuous environmental variables. This formulation is especially useful for large pedigrees, as it avoids the need to invert matrices. Whereas it may not be feasible by this method to estimate all the various components of previously suggested models for polygenic...
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