Extended pedigree patterned covariance matrix mixed models for quantitative phenotype analysis.

Abstract excerpt

Overt computational constraints in the formation of mixed models for the analysis of large extended-pedigree quantitative trait data which allow one to reliably characterize and partition sources of variation resulting from a variety sources have proven difficult to overcome. The present paper suggests that by combining a restricted patterned covariance matrix approach to modeling and partitioning the variation...

Topics

• Humans
• Models, Genetic
• Models, Statistical
• Pedigree
• Phenotype