Article
Extended pedigree patterned covariance matrix mixed models for quantitative phenotype analysis.
Genetic epidemiology - 1 Jan 1992
Schork N J
Abstract excerpt
Overt computational constraints in the formation of mixed models for the analysis of large extended-pedigree quantitative trait data which allow one to reliably characterize and partition sources of variation resulting from a variety sources have proven difficult to overcome. The present paper suggests that by combining a restricted patterned covariance matrix approach to modeling and partitioning the variation...
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