Article
The Amerindian's genes in the Mexican population are associated with development of gallstone disease.
The American journal of gastroenterology - 1 Nov 2004
Méndez-Sánchez Nahum, King-Martínez Ana Cristina, Ramos Martha H, Pichardo-Bahena Raúl, Uribe Misael
Abstract excerpt
BACKGROUND: It has been suggested that genes related to Amerindian ancestry account for the high prevalence of gallstone disease (GD) observed in Mexican-Americans. The HLA-B39 is an allele found in higher frequency in Amerindians whereas HLA-B15 is rarely found. The aim of this study was to test the hypothesis that gallstone susceptibility genes are more prevalent in Mexicans with recent Amerindian ancestry....
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